diff --git a/README.md b/README.md
index a8c655f9d..d83056a24 100644
--- a/README.md
+++ b/README.md
@@ -37,7 +37,7 @@ or type
 python setup.py install --yes USE_AVX_INSTRUCTIONS
 ```
 
-if you have a CPU that supports AVX instructions, since this makes some things run faster.
+if you have a CPU that supports AVX instructions, since this makes some things run faster.  Note that you need to have boost-python installed to compile the Python API.